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Inhibition of the TGFβ signalling pathway by cGMP and cGMP‐dependent kinase I in renal fibrosis

Agents that enhance production of nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) ameliorate the progression of renal fibrosis. However, the molecular mechanism of this process is not fully understood. We hypothesize that the antifibrotic effects of cGMP and cGMP‐dependent kinase I (cGKI...

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Dettagli Bibliografici
Pubblicato in:FEBS Open Bio
Autori principali: Schinner, Elisabeth, Wetzl, Veronika, Schramm, Andrea, Kees, Frieder, Sandner, Peter, Stasch, Johannes‐Peter, Hofmann, Franz, Schlossmann, Jens
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377407/
https://ncbi.nlm.nih.gov/pubmed/28396839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12202
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