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Efficient, low-cost protein factories: expression of human adenosine deaminase in baculovirus-infected insect larvae.

Human adenosine deaminase (EC 3.5.4.4), a key purine salvage enzyme essential for immune competence, has been overproduced in Spodoptera frugiperda cells and in Trichoplusia ni (cabbage looper) larvae infected with recombinant baculovirus. The coding sequence of human adenosine deaminase was recombi...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Medin, J A, Hunt, L, Gathy, K, Evans, R K, Coleman, M S
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53770/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2181448/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.7.2760
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