p53 expression is required for thymocyte apoptosis induced by adenosine deaminase deficiency.
Adenosine deaminase (ADA, EC 3.5.4.4) is a ubiquitous enzyme in the purine catabolic pathway. In contrast to the widespread tissue distribution of this enzyme, inherited ADA deficiency in human results in a tissue-specific severe combined immunodeficiency. To explain the molecular basis for this rem...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1995
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41159/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7667298/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.18.8373 |
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