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NDR1 protein kinase promotes IL‐17‐ and TNF‐α‐mediated inflammation by competitively binding TRAF3

Interleukin 17 (IL‐17) is an important inducer of tissue inflammation and is involved in numerous autoimmune diseases. However, how its signal transduction is regulated is not well understood. Here, we report that nuclear Dbf2‐related kinase 1 (NDR1) functions as a positive regulator of IL‐17 signal...

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Podrobná bibliografie
Vydáno v:EMBO Rep
Hlavní autoři: Ma, Chunmei, Lin, Wenlong, Liu, Zhiyong, Tang, Wei, Gautam, Rahul, Li, Hui, Qian, Youcun, Huang, He, Wang, Xiaojian
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376972/
https://ncbi.nlm.nih.gov/pubmed/28219902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642140
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