Epithelial TRAF6 drives IL-17–mediated psoriatic inflammation

Epithelial cells are the first line of defense against external dangers, and contribute to induction of adaptive immunity including Th17 responses. However, it is unclear whether specific epithelial signaling pathways are essential for the development of robust IL-17–mediated immune responses. In mi...

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Dades bibliogràfiques
Publicat a:JCI Insight
Autors principals: Matsumoto, Reiko, Dainichi, Teruki, Tsuchiya, Soken, Nomura, Takashi, Kitoh, Akihiko, Hayden, Matthew S., Ishii, Ken J., Tanaka, Mayuri, Honda, Tetsuya, Egawa, Gyohei, Otsuka, Atsushi, Nakajima, Saeko, Sakurai, Kenji, Nakano, Yuri, Kobayashi, Takashi, Sugimoto, Yukihiko, Kabashima, Kenji
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129131/
https://ncbi.nlm.nih.gov/pubmed/30089718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121175
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