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Epithelial TRAF6 drives IL-17–mediated psoriatic inflammation

Epithelial cells are the first line of defense against external dangers, and contribute to induction of adaptive immunity including Th17 responses. However, it is unclear whether specific epithelial signaling pathways are essential for the development of robust IL-17–mediated immune responses. In mi...

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Detalles Bibliográficos
Publicado en:JCI Insight
Autores principales: Matsumoto, Reiko, Dainichi, Teruki, Tsuchiya, Soken, Nomura, Takashi, Kitoh, Akihiko, Hayden, Matthew S., Ishii, Ken J., Tanaka, Mayuri, Honda, Tetsuya, Egawa, Gyohei, Otsuka, Atsushi, Nakajima, Saeko, Sakurai, Kenji, Nakano, Yuri, Kobayashi, Takashi, Sugimoto, Yukihiko, Kabashima, Kenji
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129131/
https://ncbi.nlm.nih.gov/pubmed/30089718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121175
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