Epithelial TRAF6 drives IL-17–mediated psoriatic inflammation

Epithelial cells are the first line of defense against external dangers, and contribute to induction of adaptive immunity including Th17 responses. However, it is unclear whether specific epithelial signaling pathways are essential for the development of robust IL-17–mediated immune responses. In mi...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Matsumoto, Reiko, Dainichi, Teruki, Tsuchiya, Soken, Nomura, Takashi, Kitoh, Akihiko, Hayden, Matthew S., Ishii, Ken J., Tanaka, Mayuri, Honda, Tetsuya, Egawa, Gyohei, Otsuka, Atsushi, Nakajima, Saeko, Sakurai, Kenji, Nakano, Yuri, Kobayashi, Takashi, Sugimoto, Yukihiko, Kabashima, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129131/
https://ncbi.nlm.nih.gov/pubmed/30089718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121175
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