Epithelial TRAF6 drives IL-17–mediated psoriatic inflammation

Epithelial cells are the first line of defense against external dangers, and contribute to induction of adaptive immunity including Th17 responses. However, it is unclear whether specific epithelial signaling pathways are essential for the development of robust IL-17–mediated immune responses. In mi...

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Enregistré dans:
Détails bibliographiques
Publié dans:JCI Insight
Auteurs principaux: Matsumoto, Reiko, Dainichi, Teruki, Tsuchiya, Soken, Nomura, Takashi, Kitoh, Akihiko, Hayden, Matthew S., Ishii, Ken J., Tanaka, Mayuri, Honda, Tetsuya, Egawa, Gyohei, Otsuka, Atsushi, Nakajima, Saeko, Sakurai, Kenji, Nakano, Yuri, Kobayashi, Takashi, Sugimoto, Yukihiko, Kabashima, Kenji
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129131/
https://ncbi.nlm.nih.gov/pubmed/30089718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121175
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