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NDR1 protein kinase promotes IL‐17‐ and TNF‐α‐mediated inflammation by competitively binding TRAF3

Interleukin 17 (IL‐17) is an important inducer of tissue inflammation and is involved in numerous autoimmune diseases. However, how its signal transduction is regulated is not well understood. Here, we report that nuclear Dbf2‐related kinase 1 (NDR1) functions as a positive regulator of IL‐17 signal...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Ma, Chunmei, Lin, Wenlong, Liu, Zhiyong, Tang, Wei, Gautam, Rahul, Li, Hui, Qian, Youcun, Huang, He, Wang, Xiaojian
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376972/
https://ncbi.nlm.nih.gov/pubmed/28219902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642140
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