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Mechanistic insights on the Pd-catalyzed addition of C–X bonds across alkynes – a combined experimental and computational study

The Pd-catalyzed intramolecular addition of carbamoyl chlorides and aryl halides across alkynes is investigated by means of DFT calculations and mechanistic test experiments. The data suggest a mechanistic pathway that involves oxidative addition, alkyne insertion, cis → trans isomerization and redu...

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Vydáno v:Chem Sci
Hlavní autoři: Sperger, Theresa, Le, Christine M., Lautens, Mark, Schoenebeck, Franziska
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376711/
https://ncbi.nlm.nih.gov/pubmed/28451357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc05001h
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