A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells

Individual human epidermal cells differ in their self-renewal ability. To uncover the molecular basis for this heterogeneity, we performed genome-wide pooled RNA interference screens and identified genes conferring a clonal growth advantage on normal and neoplastic (cutaneous squamous cell carcinoma...

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I publikationen:Nat Commun
Huvudupphovsmän: Walko, Gernot, Woodhouse, Samuel, Pisco, Angela Oliveira, Rognoni, Emanuel, Liakath-Ali, Kifayathullah, Lichtenberger, Beate M., Mishra, Ajay, Telerman, Stephanie B., Viswanathan, Priyalakshmi, Logtenberg, Meike, Renz, Lisa M., Donati, Giacomo, Quist, Sven R., Watt, Fiona M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376649/
https://ncbi.nlm.nih.gov/pubmed/28332498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14744
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