A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis

Epidermal homeostasis depends on a balance between stem cell renewal and terminal differentiation. The transition between the two cell states, termed commitment, is poorly understood. Here, we characterise commitment by integrating transcriptomic and proteomic data from disaggregated primary human k...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Mishra, Ajay, Oulès, Bénédicte, Pisco, Angela Oliveira, Ly, Tony, Liakath-Ali, Kifayathullah, Walko, Gernot, Viswanathan, Priyalakshmi, Tihy, Matthieu, Nijjher, Jagdeesh, Dunn, Sara-Jane, Lamond, Angus I, Watt, Fiona M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Computational and Systems Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667932/
https://ncbi.nlm.nih.gov/pubmed/29043977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27356
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