Osteogenesis Is Improved by Low Tumor Necrosis Factor Alpha Concentration through the Modulation of Gs-Coupled Receptor Signals

In the early phase of bone damage, low concentrations of the cytokine tumor necrosis factor alpha (TNF-α) favor osteoblast differentiation. In contrast, chronic high doses of the same cytokine contribute to bone loss, demonstrating opposite effects depending on its concentration and on the time of e...

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Foilsithe in:Mol Cell Biol
Main Authors: Daniele, Simona, Natali, Letizia, Giacomelli, Chiara, Campiglia, Pietro, Novellino, Ettore, Martini, Claudia, Trincavelli, Maria Letizia
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376638/
https://ncbi.nlm.nih.gov/pubmed/28137910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00442-16
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