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Osteogenesis Is Improved by Low Tumor Necrosis Factor Alpha Concentration through the Modulation of Gs-Coupled Receptor Signals
In the early phase of bone damage, low concentrations of the cytokine tumor necrosis factor alpha (TNF-α) favor osteoblast differentiation. In contrast, chronic high doses of the same cytokine contribute to bone loss, demonstrating opposite effects depending on its concentration and on the time of e...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Mol Cell Biol |
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Κύριοι συγγραφείς: | , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
American Society for Microbiology
2017
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5376638/ https://ncbi.nlm.nih.gov/pubmed/28137910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00442-16 |
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