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Derepression of the DNA Methylation Machinery of the Gata1 Gene Triggers the Differentiation Cue for Erythropoiesis

GATA1 is a critical regulator of erythropoiesis. While the mechanisms underlying the high-level expression of GATA1 in maturing erythroid cells have been studied extensively, the initial activation of the Gata1 gene in early hematopoietic progenitors remains to be elucidated. We previously identifie...

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Publicat a:Mol Cell Biol
Autors principals: Yu, Lei, Takai, Jun, Otsuki, Akihito, Katsuoka, Fumiki, Suzuki, Mikiko, Katayama, Saori, Nezu, Masahiro, Engel, James Douglas, Moriguchi, Takashi, Yamamoto, Masayuki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376630/
https://ncbi.nlm.nih.gov/pubmed/28069743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00592-16
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