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In vivo requirements for GATA-1 functional domains during primitive and definitive erythropoiesis
GATA-1 is a transcription factor essential for erythroid/megakaryocytic cell differentiation. To investigate the contribution of individual domains of GATA-1 to its activity, transgenic mice expressing either an N-terminus, or an N- or C-terminal zinc finger deletion of GATA-1 (ΔNT, ΔNF or ΔCF, resp...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125635/ https://ncbi.nlm.nih.gov/pubmed/11566888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.18.5250 |
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