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Glucose and fatty acids synergistically and reversibly promote beta cell proliferation in rats

AIMS/HYPOTHESIS: The mechanisms underlying pancreatic islet mass expansion have attracted considerable interest as potential therapeutic targets to prevent or delay the onset of type 2 diabetes. While several factors promoting beta cell proliferation have been identified, in the context of nutrient...

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Publicat a:Diabetologia
Autors principals: Moullé, Valentine S., Vivot, Kevin, Tremblay, Caroline, Zarrouki, Bader, Ghislain, Julien, Poitout, Vincent
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376373/
https://ncbi.nlm.nih.gov/pubmed/28078385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-016-4197-8
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