Atomic resolution structures from fragmented protein crystals by the cryoEM method MicroED

Crystallographic analysis of macromolecules depends on large, well-ordered crystals, which often require significant effort to obtain. Even sizable crystals sometimes suffer from pathologies that render them inappropriate for high-resolution structure determination. Here we show that fragmentation o...

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Veröffentlicht in:Nat Methods
Hauptverfasser: de la Cruz, M. Jason, Hattne, Johan, Shi, Dan, Seidler, Paul, Rodriguez, Jose, Reyes, Francis E., Sawaya, Michael R., Cascio, Duilio, Weiss, Simon C., Kim, Sun Kyung, Hinck, Cynthia S., Hinck, Andrew P., Calero, Guillermo, Eisenberg, David, Gonen, Tamir
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376236/
https://ncbi.nlm.nih.gov/pubmed/28192420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4178
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