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Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED
Electrons, because of their strong interaction with matter, produce high-resolution diffraction patterns from tiny 3D crystals only a few hundred nanometers thick in a frozen-hydrated state. This discovery offers the prospect of facile structure determination of complex biological macromolecules, wh...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5056061/ https://ncbi.nlm.nih.gov/pubmed/27647903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606287113 |
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