Overexpressed human metallothionein IIA gene protects Chinese hamster ovary cells from killing by alkylating agents.

Experiments were designed to detect survival advantages that cells gain by overexpressing metallothionein (MT). Chinese hamster ovary K1-2 cells and an x-ray-sensitive derivative were transfected with a bovine papillomavirus (BPV)-linked construct carrying the human metallothionein IIA (hMT-IIA) gen...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Kaina, B, Lohrer, H, Karin, M, Herrlich, P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53760/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2320583/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.7.2710
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