Overexpressed human metallothionein IIA gene protects Chinese hamster ovary cells from killing by alkylating agents.
Experiments were designed to detect survival advantages that cells gain by overexpressing metallothionein (MT). Chinese hamster ovary K1-2 cells and an x-ray-sensitive derivative were transfected with a bovine papillomavirus (BPV)-linked construct carrying the human metallothionein IIA (hMT-IIA) gen...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53760/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2320583/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.7.2710 |
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