Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB

The type I interferon (IFN) response is part of the first-line defense against viral infection. To initiate replication, viruses have developed powerful evasion strategies to counteract host IFN responses. In the present study, we found that the Japanese encephalitis virus (JEV) NS5 protein could in...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Ye, Jing, Chen, Zheng, Li, Yunchuan, Zhao, Zikai, He, Wen, Zohaib, Ali, Song, Yunfeng, Deng, Chenglin, Zhang, Bo, Chen, Huanchun, Cao, Shengbo
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Virus-Cell Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375679/
https://ncbi.nlm.nih.gov/pubmed/28179530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00039-17
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