Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB

The type I interferon (IFN) response is part of the first-line defense against viral infection. To initiate replication, viruses have developed powerful evasion strategies to counteract host IFN responses. In the present study, we found that the Japanese encephalitis virus (JEV) NS5 protein could in...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Ye, Jing, Chen, Zheng, Li, Yunchuan, Zhao, Zikai, He, Wen, Zohaib, Ali, Song, Yunfeng, Deng, Chenglin, Zhang, Bo, Chen, Huanchun, Cao, Shengbo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2017
Gaiak:
Virus-Cell Interactions
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375679/
https://ncbi.nlm.nih.gov/pubmed/28179530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00039-17
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