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Structure-based discovery of two antiviral inhibitors targeting the NS3 helicase of Japanese encephalitis virus

Japanese encephalitis virus (JEV) is a flavivirus that threatens more than half of the world’s population. Vaccination can prevent the disease, but no specific antiviral drug is yet available for clinical therapy, and the death rate caused by JEV can reach as high as 60%. The C-terminus of non-struc...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Fang, Jin’e, Li, Huan, Kong, Dexin, Cao, Shengbo, Peng, Guiqing, Zhou, Rui, Chen, Huanchun, Song, Yunfeng
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041104/
https://ncbi.nlm.nih.gov/pubmed/27679979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34550
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