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Crystal Structure of the Dimerized N Terminus of Porcine Circovirus Type 2 Replicase Protein Reveals a Novel Antiviral Interface
Two replicase (Rep) proteins, Rep and Rep′, are encoded by porcine circovirus (PCV) ORF1; Rep is a full ORF1 transcript, and Rep′ is a truncated transcript generated by splicing. These two proteins are crucial for the rolling-circle replication (RCR) of PCV. The N-terminal sequences of Rep and Rep′...
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| Gepubliceerd in: | J Virol |
|---|---|
| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6146719/ https://ncbi.nlm.nih.gov/pubmed/29976661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00724-18 |
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