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The Sodium Pump and Cardiotonic Steroids-Induced Signal Transduction: Protein Kinases and Calcium Signaling Microdomain in Regulation of Transporter Trafficking

The Na/K-ATPase was discovered as an energy transducing ion pump. A major difference between the Na/K-ATPase and other P-type ATPases is its ability to bind a group of chemicals called cardiotonic steroids (CTS). The plant-derived CTS such as digoxin are valuable drugs for the management of cardiac...

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Bibliographische Detailangaben
Veröffentlicht in:Biochim Biophys Acta
Hauptverfasser: Liu, Jiang, Xie, Zi-jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375027/
https://ncbi.nlm.nih.gov/pubmed/20144708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2010.01.013
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