Endogenous Cardiotonic Steroids and Differential Patterns of Sodium Pump Inhibition in NaCl-Loaded Salt-Sensitive and Normotensive Rats

BACKGROUND: Endogenous sodium pump inhibitors promote sodium excretion in normotensives and contribute to vasoconstriction in NaCl-sensitive hypertension. Marinobufagenin (MBG), an endogenous bufadienolide inhibitor of α-1 sodium pump, contributes to hypertension in Dahl salt-sensitive rats (DS). We...

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Bibliographic Details
Main Authors: Bagrov, Alexei Y., Agalakova, Natalia I., Kashkin, Vladimir A., Fedorova, Olga V.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678964/
https://ncbi.nlm.nih.gov/pubmed/19229192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajh.2009.22
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