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Endogenous Cardiotonic Steroids and Differential Patterns of Sodium Pump Inhibition in NaCl-Loaded Salt-Sensitive and Normotensive Rats
BACKGROUND: Endogenous sodium pump inhibitors promote sodium excretion in normotensives and contribute to vasoconstriction in NaCl-sensitive hypertension. Marinobufagenin (MBG), an endogenous bufadienolide inhibitor of α-1 sodium pump, contributes to hypertension in Dahl salt-sensitive rats (DS). We...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678964/ https://ncbi.nlm.nih.gov/pubmed/19229192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajh.2009.22 |
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