LRIT3 Differentially Affects Connectivity and Synaptic Transmission of Cones to ON- and OFF-Bipolar Cells

PURPOSE: Mutations in LRIT3 lead to complete congenital stationary night blindness (cCSNB). Using a cCSNB mouse model lacking Lrit3 (nob6), we recently have shown that LRIT3 has a role in the correct localization of TRPM1 (transient receptor potential melastatin 1) to the dendritic tips of ON-bipola...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Neuillé, Marion, Cao, Yan, Caplette, Romain, Guerrero-Given, Debbie, Thomas, Connon, Kamasawa, Naomi, Sahel, José-Alain, Hamel, Christian P., Audo, Isabelle, Picaud, Serge, Martemyanov, Kirill A., Zeitz, Christina
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2017
Assuntos:
Visual Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374884/
https://ncbi.nlm.nih.gov/pubmed/28334377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20745
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