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LRIT3 is essential to localize TRPM1 to the dendritic tips of depolarizing bipolar cells and may play a role in cone synapse formation
Mutations in LRIT3 lead to complete congenital stationary night blindness (cCSNB). The exact role of LRIT3 in ON-bipolar cell signaling cascade remains to be elucidated. Recently, we have characterized a novel mouse model lacking Lrit3 (no b-wave 6, (Lrit3(nob6/nob6))), which displays similar abnorm...
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| Udgivet i: | Eur J Neurosci |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4733627/ https://ncbi.nlm.nih.gov/pubmed/25997951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12959 |
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