Chargement en cours...
A multi-functional AAV-CRISPR-Cas9 and its host response
CRISPR-Cas9 delivery by AAV holds promise for gene therapy but faces critical barriers due to its potential immunogenicity and limited payload capacity. Here, we demonstrate genome engineering in postnatal mice using AAV-split-Cas9, a multi-functional platform customizable for genome-editing, transc...
Enregistré dans:
| Publié dans: | Nat Methods |
|---|---|
| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5374744/ https://ncbi.nlm.nih.gov/pubmed/27595405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3993 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|