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Severe pre-eclampsia is associated with alterations in cytotrophoblasts of the smooth chorion

Pre-eclampsia (PE), which affects ∼8% of first pregnancies, is associated with faulty placentation. Extravillous cytotrophoblasts (CTBs) fail to differentiate properly, contributing to shallow uterine invasion and deficient spiral artery remodeling. We studied the effects of severe PE (sPE) on the s...

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Détails bibliographiques
Publié dans:Development
Auteurs principaux: Garrido-Gomez, Tamara, Ona, Katherine, Kapidzic, Mirhan, Gormley, Matthew, Simón, Carlos, Genbacev, Olga, Fisher, Susan J.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374356/
https://ncbi.nlm.nih.gov/pubmed/28232601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.146100
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