Severe pre-eclampsia is associated with alterations in cytotrophoblasts of the smooth chorion

Pre-eclampsia (PE), which affects ∼8% of first pregnancies, is associated with faulty placentation. Extravillous cytotrophoblasts (CTBs) fail to differentiate properly, contributing to shallow uterine invasion and deficient spiral artery remodeling. We studied the effects of severe PE (sPE) on the s...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Development
Main Authors: Garrido-Gomez, Tamara, Ona, Katherine, Kapidzic, Mirhan, Gormley, Matthew, Simón, Carlos, Genbacev, Olga, Fisher, Susan J.
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2017
Teme:
Human Development
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374356/
https://ncbi.nlm.nih.gov/pubmed/28232601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.146100
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