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Severe pre-eclampsia is associated with alterations in cytotrophoblasts of the smooth chorion

Pre-eclampsia (PE), which affects ∼8% of first pregnancies, is associated with faulty placentation. Extravillous cytotrophoblasts (CTBs) fail to differentiate properly, contributing to shallow uterine invasion and deficient spiral artery remodeling. We studied the effects of severe PE (sPE) on the s...

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Bibliografiska uppgifter
I publikationen:Development
Huvudupphovsmän: Garrido-Gomez, Tamara, Ona, Katherine, Kapidzic, Mirhan, Gormley, Matthew, Simón, Carlos, Genbacev, Olga, Fisher, Susan J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Company of Biologists Ltd 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374356/
https://ncbi.nlm.nih.gov/pubmed/28232601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.146100
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