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Efficient TALEN-mediated gene targeting of chicken primordial germ cells
In this work we use TALE nucleases (TALENs) to target a reporter construct to the DDX4 (vasa) locus in chicken primordial germ cells (PGCs). Vasa is a key germ cell determinant in many animal species and is posited to control avian germ cell formation. We show that TALENs mediate homology-directed r...
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| Pubblicato in: | Development |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Company of Biologists Ltd
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5374353/ https://ncbi.nlm.nih.gov/pubmed/28174243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.145367 |
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