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FGF, Insulin, and SMAD Signaling Cooperate for Avian Primordial Germ Cell Self-Renewal

Precise self-renewal of the germ cell lineage is fundamental to fertility and reproductive success. The early precursors for the germ lineage, primordial germ cells (PGCs), survive and proliferate in several embryonic locations during their migration to the embryonic gonad. By elucidating the active...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Whyte, Jemima, Glover, James D., Woodcock, Mark, Brzeszczynska, Joanna, Taylor, Lorna, Sherman, Adrian, Kaiser, Pete, McGrew, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682126/
https://ncbi.nlm.nih.gov/pubmed/26677769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.10.008
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