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Activation of PPARγ by endogenous prostaglandin J(2) mediates the antileukemic effect of selenium in murine leukemia
Supplementation with nontoxic doses of micronutrient selenium has been shown to alleviate chronic myelogenous leukemia (CML) via the elimination of leukemia stem cells (LSCs) in mice. This treatment provides a new and novel method for eliminating the LSCs that are otherwise not targeted by existing...
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| Udgivet i: | Blood |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5374288/ https://ncbi.nlm.nih.gov/pubmed/28115365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-08-736405 |
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