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Activation of PPARγ by endogenous prostaglandin J(2) mediates the antileukemic effect of selenium in murine leukemia

Supplementation with nontoxic doses of micronutrient selenium has been shown to alleviate chronic myelogenous leukemia (CML) via the elimination of leukemia stem cells (LSCs) in mice. This treatment provides a new and novel method for eliminating the LSCs that are otherwise not targeted by existing...

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Publicado no:Blood
Main Authors: Finch, Emily R., Tukaramrao, Diwakar B., Goodfield, Laura L., Quickel, Michael D., Paulson, Robert F., Prabhu, K. Sandeep
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374288/
https://ncbi.nlm.nih.gov/pubmed/28115365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-08-736405
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