Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria

Cerebral malaria is a deadly outcome of infection by Plasmodium falciparum, occurring when parasite-infected erythrocytes accumulate in the brain. These erythrocytes display parasite proteins of the PfEMP1 family that bind various endothelial receptors. Despite the importance of cerebral malaria, a...

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Publicado no:Cell Host Microbe
Main Authors: Lennartz, Frank, Adams, Yvonne, Bengtsson, Anja, Olsen, Rebecca W., Turner, Louise, Ndam, Nicaise T., Ecklu-Mensah, Gertrude, Moussiliou, Azizath, Ofori, Michael F., Gamain, Benoit, Lusingu, John P., Petersen, Jens E.V., Wang, Christian W., Nunes-Silva, Sofia, Jespersen, Jakob S., Lau, Clinton K.Y., Theander, Thor G., Lavstsen, Thomas, Hviid, Lars, Higgins, Matthew K., Jensen, Anja T.R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374107/
https://ncbi.nlm.nih.gov/pubmed/28279348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.02.009
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