Insect cells are superior to Escherichia coli in producing malaria proteins inducing IgG targeting PfEMP1 on infected erythrocytes

BACKGROUND: The PFD1235w Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) antigen is associated with severe malaria in children and can be expressed on the surface of infected erythrocytes (IE) adhering to ICAM1. However, the exact three-dimensional structure of this PfEMP1 and its surf...

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Main Authors: Victor, Michala E, Bengtsson, Anja, Andersen, Gorm, Bengtsson, Dominique, Lusingu, John P, Vestergaard, Lasse S, Arnot, David E, Theander, Thor G, Joergensen, Louise, Jensen, Anja TR
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994891/
https://ncbi.nlm.nih.gov/pubmed/21078147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-9-325
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