M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza

In each influenza season, a distinct group of young, otherwise healthy individuals with no risk factors succumbs to life-threatening infection. To better understand the cause for this, we analyzed a broad range of immune responses in blood from a unique cohort of patients, comprising previously heal...

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Publicado en:JCI Insight
Autores principales: Cole, Suzanne L., Dunning, Jake, Kok, Wai Ling, Benam, Kambez Hajipouran, Benlahrech, Adel, Repapi, Emmanouela, Martinez, Fernando O., Drumright, Lydia, Powell, Timothy J., Bennett, Michael, Elderfield, Ruth, Thomas, Catherine, Dong, Tao, McCauley, John, Liew, Foo Y., Taylor, Stephen, Zambon, Maria, Barclay, Wendy, Cerundolo, Vincenzo, Openshaw, Peter J., McMichael, Andrew J., Ho, Ling-Pei
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374077/
https://ncbi.nlm.nih.gov/pubmed/28405622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91868
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