Preconditioned mesenchymal stem cells treat myasthenia gravis in a humanized preclinical model

Myasthenia gravis (MG) with anti–acetylcholine receptor (AChR) Abs is an autoimmune disease characterized by severe defects in immune regulation and thymic inflammation. Because mesenchymal stem cells (MSCs) display immunomodulatory features, we investigated whether and how in vitro–preconditioned h...

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Vydáno v:JCI Insight
Hlavní autoři: Sudres, Muriel, Maurer, Marie, Robinet, Marieke, Bismuth, Jacky, Truffault, Frédérique, Girard, Diane, Dragin, Nadine, Attia, Mohamed, Fadel, Elie, Santelmo, Nicola, Sicsic, Camille, Brenner, Talma, Berrih-Aknin, Sonia
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374074/
https://ncbi.nlm.nih.gov/pubmed/28405609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89665
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