Preconditioned mesenchymal stem cells treat myasthenia gravis in a humanized preclinical model

Myasthenia gravis (MG) with anti–acetylcholine receptor (AChR) Abs is an autoimmune disease characterized by severe defects in immune regulation and thymic inflammation. Because mesenchymal stem cells (MSCs) display immunomodulatory features, we investigated whether and how in vitro–preconditioned h...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Sudres, Muriel, Maurer, Marie, Robinet, Marieke, Bismuth, Jacky, Truffault, Frédérique, Girard, Diane, Dragin, Nadine, Attia, Mohamed, Fadel, Elie, Santelmo, Nicola, Sicsic, Camille, Brenner, Talma, Berrih-Aknin, Sonia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374074/
https://ncbi.nlm.nih.gov/pubmed/28405609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89665
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