T cells control the generation of nanomolar-affinity anti-glycan antibodies

Vaccines targeting glycan structures at the surface of pathogenic microbes must overcome the inherent T cell–independent nature of immune responses against glycans. Carbohydrate conjugate vaccines achieve this by coupling bacterial polysaccharides to a carrier protein that recruits heterologous CD4...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Polonskaya, Zinaida, Deng, Shenglou, Sarkar, Anita, Kain, Lisa, Comellas-Aragones, Marta, McKay, Craig S., Kaczanowska, Katarzyna, Holt, Marie, McBride, Ryan, Palomo, Valle, Self, Kevin M., Taylor, Seth, Irimia, Adriana, Mehta, Sanjay R., Dan, Jennifer M., Brigger, Matthew, Crotty, Shane, Schoenberger, Stephen P., Paulson, James C., Wilson, Ian A., Savage, Paul B., Finn, M.G., Teyton, Luc
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373877/
https://ncbi.nlm.nih.gov/pubmed/28287405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI91192
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