Metabolic Imaging of Glutamine in Cancer

Glucose and glutamine are the most abundant nutrients for producing energy and building blocks in normal and tumor cells. Increased glycolysis in tumors, the Warburg Effect, is the basis for (18)F-FDG PET imaging. Cancer cells can also be genetically reprogrammed to use glutamine. 5-(11)C-(2S)-gluta...

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Bibliografiske detaljer
Udgivet i:J Nucl Med
Main Authors: Zhu, Lin, Ploessl, Karl, Zhou, Rong, Mankoff, David, Kung, Hank F.
Format: Artigo
Sprog:Inglês
Udgivet: Society of Nuclear Medicine 2017
Fag:
Focus on Molecular Imaging
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373500/
https://ncbi.nlm.nih.gov/pubmed/28232608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.116.182345
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