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Most ApoL1 Is Secreted by the Liver

Two coding sequence variants in the APOL1 gene (G1 and G2) explain much of the increased risk for FSGS, HIV-associated nephropathy, and hypertension-attributed ESRD among people of recent African ancestry. The ApoL1 protein is expressed in a wide variety of cell tissues. It has been assumed that the...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Shukha, Khuloud, Mueller, Jessica L., Chung, Raymond T., Curry, Michael P., Friedman, David J., Pollak, Martin R., Berg, Anders H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373451/
https://ncbi.nlm.nih.gov/pubmed/27932478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016040441
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