Association of Trypanolytic ApoL1 Variants with Kidney Disease in African-Americans

African-Americans have higher rates of kidney disease than European-Americans. Here we show that in African-Americans, focal segmental glomerulosclerosis (FSGS) and hypertension-attributed end-stage kidney disease (H-ESKD) are associated with two independent sequence variants in the APOL1 gene on ch...

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Main Authors: Genovese, Giulio, Friedman, David J., Ross, Michael D., Lecordier, Laurence, Uzureau, Pierrick, Freedman, Barry I., Bowden, Donald W., Langefeld, Carl D., Oleksyk, Taras K., Knob, Andrea Uscinski, Bernhardy, Andrea J., Hicks, Pamela J., Nelson, George W., Vanhollebeke, Benoit, Winkler, Cheryl A., Kopp, Jeffrey B., Pays, Etienne, Pollak, Martin R.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980843/
https://ncbi.nlm.nih.gov/pubmed/20647424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1193032
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