Ablation of cytochrome P450 omega-hydroxylase 4A14 gene attenuates hepatic steatosis and fibrosis

Nonalcoholic fatty liver disease (NAFLD) is characterized by simple hepatic steatosis (SS), nonalcoholic steatohepatitis (NASH), hepatic fibrosis, and cirrhosis. Dysregulated fatty acid metabolism in the liver plays a critical role in the pathogenesis of NAFLD. Cytochrome P450 omega-hydroxylase 4A14...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Zhang, Xiaoyan, Li, Sha, Zhou, Yunfeng, Su, Wen, Ruan, Xiongzhong, Wang, Bing, Zheng, Feng, Warner, Margaret, Gustafsson, Jan-Åke, Guan, Youfei
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373383/
https://ncbi.nlm.nih.gov/pubmed/28270609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700172114
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