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Cytochrome P450 Omega-Hydroxylase 4a14 Attenuates Cholestatic Liver Fibrosis

BACKGROUND: Cholestasis is a pathological condition involving obstruction of bile secretion and excretion that results in hepatotoxicity, inflammation, fibrosis, cirrhosis, and eventually liver failure. Common bile duct ligation (BDL) model is a well-established murine model to mimic cholestatic liv...

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Bibliografske podrobnosti
izdano v:Front Physiol
Main Authors: Li, Sha, Wang, Chenghai, Zhang, Xiaxia, Su, Wen
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201794/
https://ncbi.nlm.nih.gov/pubmed/34135776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.688259
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