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Clinical concentrations of chemically diverse general anesthetics minimally affect lipid bilayer properties

General anesthetics have revolutionized medicine by facilitating invasive procedures, and have thus become essential drugs. However, detailed understanding of their molecular mechanisms remains elusive. A mechanism proposed over a century ago involving unspecified interactions with the lipid bilayer...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Herold, Karl F., Sanford, R. Lea, Lee, William, Andersen, Olaf S., Hemmings, Hugh C.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373365/
https://ncbi.nlm.nih.gov/pubmed/28265069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611717114
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