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Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties

Although general anesthetics are clinically important and widely used, their molecular mechanisms of action remain poorly understood. Volatile anesthetics such as isoflurane (ISO) are thought to alter neuronal function by depressing excitatory and facilitating inhibitory neurotransmission through di...

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Библиографические подробности
Опубликовано в: :J Gen Physiol
Главные авторы: Herold, Karl F., Sanford, R. Lea, Lee, William, Schultz, Margaret F., Ingólfsson, Helgi I., Andersen, Olaf S., Hemmings, Hugh C.
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242807/
https://ncbi.nlm.nih.gov/pubmed/25385786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411172
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