Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties

Although general anesthetics are clinically important and widely used, their molecular mechanisms of action remain poorly understood. Volatile anesthetics such as isoflurane (ISO) are thought to alter neuronal function by depressing excitatory and facilitating inhibitory neurotransmission through di...

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Publicado en:J Gen Physiol
Autores principales: Herold, Karl F., Sanford, R. Lea, Lee, William, Schultz, Margaret F., Ingólfsson, Helgi I., Andersen, Olaf S., Hemmings, Hugh C.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242807/
https://ncbi.nlm.nih.gov/pubmed/25385786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411172
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