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Gramicidin-based Fluorescence Assay; for Determining Small Molecules Potential for Modifying Lipid Bilayer Properties

Many drugs and other small molecules used to modulate biological function are amphiphiles that adsorb at the bilayer/solution interface and thereby alter lipid bilayer properties. This is important because membrane proteins are energetically coupled to their host bilayer by hydrophobic interactions....

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Autori principali: Ingólfsson, Helgi I., Sanford, R. Lea, Kapoor, Ruchi, Andersen, Olaf S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185632/
https://ncbi.nlm.nih.gov/pubmed/20972414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2131
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