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Screening for Small Molecules' Bilayer-Modifying Potential Using a Gramicidin-Based Fluorescence Assay

Many drugs and other small molecules used to modulate biological function are amphiphiles that adsorb at the bilayer/solution interface and thereby alter lipid bilayer properties. This is important because membrane proteins are energetically coupled to their host bilayer by hydrophobic interactions....

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Bibliografische gegevens
Hoofdauteurs: Ingólfsson, Helgi I., Andersen, Olaf S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc. 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929145/
https://ncbi.nlm.nih.gov/pubmed/20233091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2009.0250
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